Summary: In the article titled, “Abnormal Cortex Plasticity in Juvenile Myoclonic Epilepsy”, the authors investigate the role of defective motor plasticity in the pathogenesis of Juvenile Myoclonic Epilepsy (Strigaro et al.). Prior to this study, JME was linked to motor cortex hyper-excitability and to the abnormal function of thalamic networks. This study, identifies a new mechanism that can cause JME, a common form of generalized epilepsy seen in children. The motor cortex plasticity was studied using an interesting technique called the Paired Associated Stimulation (PAS). The details of this technique are discussed in the methodology section. The role of ...
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Over the past few years, there has been a growing interest among neurosurgeons on the potential for therapies that impact on diseases, over and above the movement disorders and pain. One of the biggest targets of this increasing interest has been the nucleus accumbens. It has been studied for long, as an area of the brain that mediates a variety of behaviors, including reward and satisfaction (Salgado & Kaplitt, 2015). With this in mind, the modulation of the biology of the Nucleus Accumbens through either deep brain stimulation or through biological therapies like gene therapy or the transplantation of cells ...
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