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Introduction and Literature Review
The value for a drug is significantly impacted by the dissolution rate, chemical stability and solubility of the drugs thereby impacting the pharmaceuticals efficiency as well. In the pharmaceutical industry multi-component crystals such as hydrates, solvates, co-crystals and salts have a major role during the design of new solids. Solid does not self-crystallize. It crystallizes in varied forms depicting random crystal properties. Various approaches are used to modify solids like Salting, Solvation, Hydration, and Polymorphism. Apart from these approaches, Co-Crystallization is a promising new approach to modifying solids (Nauha, ...