Essays on Thyroxine

Rat Endocrinology

Hypothalamus 1. What is the molecular mechanism to release TRH? TRH refers to the thyrotropin-releasing hormone. This hormone is produced by the hypothalamus. Before the full activity of TRH, some tightly controlled processes occur in the body including the appropriate folding of prohormone to move to the secretary pathway, the processing after translation, and movement of the peptides, which are processed, towards the secretary granules for secretion (Nillni n.p.). TRH develops from bigger inactive precursor (known as proTRH) as a result of modifications after translation and moved through the controlled secretary pathway. Prohormone convertases (abbreviated as PCs) including PC1/3 ...

Surgical Anesthesia

Pharmacology and Indications Licocaine Licocaine is a type of medication used with an aim of numbing tissues and nerves within a given area of the body, which provides that anesthetic effect for the body. The most popular brand names for this particular drug are xylocaine and lignocaine. Some of the common effects associated with this particular medication include drowsiness, muscle twitching, nausea, and confusion (1). The severity of the side effects depends wholly on a patient’s reaction to the chemical composition of the drug. Regarding its mode of action, licocaine works by blocking the voltage-gated Na+ channels, which ...

Based on the initial symptoms, the patient most likely suffers from hypothyroidism or low thyroid hormone disorder. Further clinical tests and an examination of the family’s medical history reveals that the particular disorder could be Hashimoto’s disease; also called Hashimoto thyroiditis. Hashimoto thyroiditis is classified as an autoimmune disease. In autoimmune disease, one's immune system attacks the body’s tissue specifically the thyroid gland (Skugor & Wilder, 2006, p.2). By attacking the thyroid gland, the disease reduces the gland’s ability to produce thyroid hormones of substantial quantity. This condition leads to hypothyroidism. Thyroid hormone deficiency presents with ...