The single-celled parasite, Plasmodium falciparum, causes malaria, was responsible for 214 million cases and 438,000 deaths globally in 2015, of which 88% of cases and 90% of deaths occurred in sub-Saharan Africa. The morphology of P. falciparum is characterized by numerous rings (young trophozoites) and the absence of mature trophozoites and schizonts. In a P. falciparum blood smear, multiple infected erythrocytes appear more often than in other species and the rings of the parasite in the blood smear tend to be smaller than other species. Distinctive crescent-shaped gametocytes appear late in the infection. In vitro cultivation of P. ...
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