(Author’s affiliation) Diabetes is a polygenic disease characterized by significantly higher levels of glucose in the blood. In this disorder, metabolic disorders lead to persistent thirst (polydipsia) and excessive level of urination (polyuria). Diabetes is caused by insulin-related disturbances in the body. In healthy human beings, pancreatic β cells have insulin that is found as a hexamer having three insulin dimers attached together by two central zinc ions. The insulin monomer has a 21-residue A chain as well as a 30-residue B chain. These chains are cross-linked by two disulfide bridges, i.e. CysA20-CysB19 and CysA7-CysB7. There is also a ...
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Overview of Abdomen
The abdomen is assessed using inspection, auscultation and palpation (White 2005). The abdomen is inspected for size and symmetry and is normally rounded, symmetric, protuberant, and soft because of weak abdominal musculature with a slightly greater diameter above the umbilicus than below. The subcutaneous blood vessels in the abdomen may appear distended and blue (Williams & Wilkins 2006).
Abdominal assessment is complex, largely because of the many vital organs and blood vessels within the cavity of abdomen and its life-sustaining functions, such as digestion and elimination that are performed here (Weber & Kelley 2009). The abdomen houses the several body ...