Humankind records show that one of the oldest beverage in existence to date is beer. Beer can be described as an intoxicating beverage produced by a process called fermentation. There is also an array of types of beers, this dictated by the different methods of preparation, raw materials and flavours included in brewing. The types of beer’s are as follows; ales, lagers, stouts and porters as well as malts. The consumption of a beer in a local bar begins from the brewery which acquire necessary resources, convert them to the taste akin the type and flavor of beer ...
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Section 1: Introductory Concepts
1. Discuss the roles of the Therapeutic Goods Administration (TGA) and the Pharmaceutical Benefits Scheme (PBS) in the provision of drugs. The role of the Therapeutic Goods Administration (TGA) is to assess the therapeutic goods available in Australia, monitoring them and measuring the standards in which they are being made (PBS, 2011). Furthermore, the TGA ensures that therapeutic advances are made accessedible to the public quickly but safely. The Pharmaceutical Benefits Scheme (PBS) is a scheme that enmakes sures that Australians throughout the country are provided access to the medicines that they need, through the administration of health care ...
Section 2. Drug Metabolism
1. i. Referring to the primary literature, investigate the metabolism of paracetamol; Using a diagram as an aid, explain the metabolism of paracetamol noting the types of reaction (functionalisation, conjugation) and enzyme families (CYP, UGT, SULT) involved in these pathways. There are two primary metabolic pathways for paracetamol within the liver – the first and most common is glucuronidation, wherein the paracetamol binds to the glucuronic acid enzyme. Sulfation, which accounts for most of the rest of these occasions, has the paracetamol combining with a sulphate to form a nontoxic conjugate (Hendrickson et al., 2006). (Hendrickson e al., 2006) ii. ...